Does N-Carboxymethyl Lysine Serve as a Prognostic Biomarker of Diabetic Nephropathy?
نویسندگان
چکیده
منابع مشابه
Smad1 as a biomarker for diabetic nephropathy.
Diabetic nephropathy is one of the most devastating complications of diabetes and develops in about one-third of diabetic patients. Exposure to a hyperglycemic environment with coexisting obesity, metabolic syndrome, hyperfiltration, hypertension, and hyperlipidemia plays a critical role in the development of diabetic nephropathy (1,2). Clinical trials demonstrated that improving glycemic contr...
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BACKGROUND Activation of the renin-angiotensin-aldosterone system (RAAS) is an important mediator of diabetic nephropathy. Urinary angiotensinogen, a novel biomarker of the intrarenal RAAS, is associated with progressive kidney injury. In this study, the authors investigated the determinants of urinary angiotensinogen and its associations with staging of diabetic nephropathy. METHODS Random u...
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L. Lu, G. Lee, V. Gulani, J. Sedor, K. Dell, and C. Flask Department of Radiology, Case Western Reserve University, Cleveland, OH, United States, Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, Department of Medicine, Case Western Reserve University, Cleveland, OH, United States, Rammelkamp Renal Research Center, MetroHealth Medical Center, C...
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AIMS/INTRODUCTION Diabetic nephropathy is one of the leading causes of end-stage renal disease. Unfortunately, reliable surrogate markers for predicting the prognostic outcome of diabetic nephropathy are as yet absent. In order to find new markers in predicting the progression of diabetic nephropathy, we carried out a prospective study by investigating the correlation between serum metabolites ...
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ژورنال
عنوان ژورنال: JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
سال: 2021
ISSN: 2249-782X
DOI: 10.7860/jcdr/2021/46489.14575